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ABC3A Polyclonal Antibody

CAT: 0965-JOT-AP05897-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05897-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster| thought to result from gene duplication| on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity| by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines| which leads to DNA degradation. However| other mechanisms are also thought to be involved| as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
Probable DNA dC->dU-editing enzyme APOBEC-3A ;EC 3.5.4.-;Phorbolin-1
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 80-160
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG