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PSB11 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP12200-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP12200-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Proteasomes generate peptides that are presented by major histocompatibility complex (MHC) I molecules to other cells of the immune system. Proteolysis is conducted by 20S proteasomes| complexes of 28 subunits arranged as a cylinder in 4 heteroheptameric rings: alpha-1 to -7| beta-1 to -7| beta-1 to -7| and alpha-1 to -7. The catalytic subunits are beta-1 (PSMB6; MIM 600307)| beta-2 (PSMB7; MIM 604030)| and beta-5 (PSMB5; MIM 600306). Three additional subunits| beta-1i (PSMB9; MIM 177045)| beta-2i (PSMB10; MIM 176847)| and beta-5i (PSMB8; MIM 177046)| are induced by gamma-interferon (IFNG; MIM 147570) and are preferentially incorporated into proteasomes to make immunoproteasomes. PSMB11| or beta-5t| is a catalytic subunit expressed exclusively in cortical thymic epithelial cells (Murata et al.| 2007
CAS Number
9007-83-4
Synonyms
PSB11
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human PSB11
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
33000
Antibody Type
Primary antibody
Isotype
IgG

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