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PSB10 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP12199-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP12199-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome| the immunoproteasome| is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family| also known as the T1B family| that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon| and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome.
CAS Number
9007-83-4
Synonyms
PSB10
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human PSB10
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
30030
Antibody Type
Primary antibody
Isotype
IgG