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NOTCH4 (Cleaved-Val1467) Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP03845-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP03845-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats| and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular| renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants| at least one of which
CAS Number
9007-83-4
Synonyms
NOTCH4 ;Cleaved-Val1467; Neurogenic locus notch homolog protein 4; Notch 4; hNotch4; Notch 4 extracellular truncation; Notch 4 intracellular domain;
Host
Rabbit
Reactivity
Human, Monkey
Immunogen
Synthesized peptide derived from human NOTCH4 (Cleaved-Val1467)
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
220330
Antibody Type
Primary antibody
Isotype
IgG