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LRP5 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP11137-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP11137-01Size:20 µL
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Background
This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
LRP5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human LRP5
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
177650
Antibody Type
Primary antibody
Isotype
IgG

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