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ITGAV Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP03164-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP03164-01Size:20 µL
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Background
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1| beta 3| beta 5| beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
CAS Number
9007-83-4
Synonyms
ITGAV ;light chain; Cleaved-Asp891; Integrin alpha-V; Vitronectin receptor subunit alpha; CD antigen CD51; Integrin alpha-V heavy chain; Integrin alpha-V light chain;
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human ITGAV (light chain| Cleaved-Asp891)
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
115280
Antibody Type
Primary antibody
Isotype
IgG