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DSC1 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP02314-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02314-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members| along with the desmogleins| are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus| a life-threatening autoimmune disease| is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein.
CAS Number
9007-83-4
Synonyms
DSC1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human DSC1
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
98340
Antibody Type
Primary antibody
Isotype
IgG