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DR5 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP09336-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP09336-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the TNF-receptor superfamily| and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L)| and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD| a death domain containing adaptor protein| is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
CAS Number
9007-83-4
Synonyms
DR5; Tumor necrosis factor receptor superfamily member 10B; Death receptor 5; TNF-related apoptosis-inducing ligand receptor 2; TRAIL receptor 2; TRAIL-R2; CD antigen CD262
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human DR5
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
48400
Antibody Type
Primary antibody
Isotype
IgG