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IF6 Polyclonal Antibody

CAT: 0965-JOT-AP08661-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP08661-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4)| a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein| which is insoluble and found both in the nucleus and in the cytoplasm| can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
Eukaryotic translation initiation factor 6 ;eIF-6;B;2GCN homolog;B4 integrin interactor;CAB;p27;BBP
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human protein . at AA range: 180-260
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG