Raf-B(Phospho Ser446) Polyclonal Antibody

CAT: 0965-JOT-AP07784-01Size: 20 µLDry Ice: NoHazardous: No

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CAT#:0965-JOT-AP07784-01Size:20 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway| which affects cell division| differentiation| and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome| a disease characterized by heart defects| mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers| including non-Hodgkin lymphoma| colorectal cancer| malignant melanoma| thyroid carcinoma| non-small cell lung carcinoma| and adenocarcinoma of lung. A pseudogene| which is located on chromosome X| has been identified for this gene.

CAS Number

9007-83-4

Synonyms

Serine/threonine-protein kinase B-raf; BRAF; BRAF1; RAFB1; Serine/threonine-protein kinase B-raf; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human B-RAF around the phosphorylation site of Ser446. AA range:411-460

Clonality

Polyclonal

Applications

WB, IHC-p, IF, ELISA

Stability

-20°C for 1 year

Concentration

1 mg/ml

Molecular Weight

84437

Antibody Type

Primary antibody

Isotype

IgG

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MBS8520554-01	Raf-B (phospho Ser446) Polyclonal Antibody
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Raf-B(Phospho Ser446) Polyclonal Antibody

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