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BBS7 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP06281-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP06281-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes one of eight proteins that form the BBSome complex containing BBS1| BBS2| BBS4| BBS5| BBS7| BBS8| BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6| BBS10| and BBS12) and CCT/TRiC family chaperonins. Mutations in this gene are implicated in Bardet-Biedl syndrome| a genetic disorder whose symptoms include obesity| retinal degeneration| polydactyly and nephropathy; however| mutations in this gene and the BBS8 gene are thought to play a minor role and mutations in chaperonin-like BBS genes are found to be a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Two transcript variants encoding distinct isoforms have been identified for this gene.
CAS Number
9007-83-4
Synonyms
BBS7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human BBS7
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
78650
Antibody Type
Primary antibody
Isotype
IgG

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