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DUSP4 Polyclonal Antibody

CAT: 0965-JOT-AP05958-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05958-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK| SAPK/JNK| p38)| which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases| different tissue distribution and subcellular localization| and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1| ERK2 and JNK| is expressed in a variety of tissues| and is localized in the nucleus. Two alternatively spliced transcript variants| encoding distinct isoforms| have been obser
CAS Number
9007-83-4
Synonyms
Dual specificity protein phosphatase 4;EC 3.1.3.16;EC 3.1.3.48;Dual specificity protein phosphatase hVH2;Mitogen-activated protein kinase phosphatase 2;MAP kinase phosphatase 2;MKP-2; Dual specificity protein phosphatase 4; EC 3.1.3.16; EC 3.1.3.48; Dual specificity protein phosphatase hVH2; Mitogen-activated protein kinase phosphatase 2; MAP kinase phosphatase 2; MKP-2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human DUSP4 Polyclonal
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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