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APOB Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP05823-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05823-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms| apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single| very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA)| resulting in the creation of a stop codon| and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia| normotriglyceridemic hypobetalipoproteinemia| and hypercholesterolemia due to ligand-defective apoB| diseases affecting plasma cholesterol and apoB levels.
CAS Number
9007-83-4
Synonyms
APOB; Apolipoprotein B-100; Apo B-100; Apolipoprotein B-48; Apo B-48;
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human APOB
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
501930
Antibody Type
Primary antibody
Isotype
IgG

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