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CDH3 Polyclonal Antibody

CAT: 0965-JOT-AP01449-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP01449-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants| at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats| a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition| aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia| ectrodactyly| and macular dystrophy syndrome (EEMS).
CAS Number
9007-83-4
Synonyms
Cadherin-3 ;Placental cadherin;P-cadherin; Cadherin-3; Placental cadherin; P-cadherin
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human CDH3 Polyclonal
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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