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CCR5 Polyclonal Antibody

CAT: 0965-JOT-AP00283-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP00283-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the beta chemokine receptor family| which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages| and is known to be an important co-receptor for macrophage-tropic virus| including HIV| to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2)| macrophage inflammatory protein 1 alpha (MIP-1 alpha)| macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line| suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemok
CAS Number
9007-83-4
Synonyms
CCR5; C-C chemokine receptor type 5; C-C CKR-5; CC-CKR-5; CCR-5; CCR5; CHEMR13; HIV-1 fusion coreceptor; CD antigen CD195
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human CCR5 Polyclonal
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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