Products for Research Use Only
RegisterLogin

Phospho-BRCA2 (S3291) Polyclonal Antibody

CAT: 0965-JOT-PHS00512-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0965-JOT-PHS00512-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.
CAS Number
9007-83-4
Synonyms
BRCA2; FACD; FANCD1; Breast cancer type 2 susceptibility protein; Fanconi anemia group D1 protein
Host
Rabbit
Reactivity
Human;mouse;rat
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human BRCA2 (phospho Ser3291)
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
384225
Antibody Type
Primary antibody
Isotype
IgG

Related Products

CatalogName
JOT-AP00969-01BRCA2 Polyclonal Antibody
JOT-PHS00038-01Phospho-BRCA1 (S1423) Polyclonal Antibody
JOT-PHS00039-01Phospho-BRCA1 (S1524) Polyclonal Antibody
JOT-PHS00462-01Phospho-BRCA1 (S1457) Polyclonal Antibody
JOT-AP06585-01BRCA1(Phospho Ser988) Rabbit Polyclonal Antibody
JOT-AP15722-01Zyxin(Phospho Ser142) Polyclonal Antibody
JOT-AP15585-01YAP(Phospho Ser127) Polyclonal Antibody
JOT-AP15630-01ZFP598(Phospho Tyr306) Polyclonal Antibody
JOT-AP14302-01Smad3(Phospho Ser213) Polyclonal Antibody
JOT-AP15430-01Vav(Phospho Tyr160) Polyclonal Antibody

Alternative Products

CatalogName
CSB-PA050157-01Phospho-BRCA2 (S3291) Antibody
BT-PHS00512-01Phospho-BRCA2 (S3291) Polyclonal Antibody
A00009S3291Anti-Phospho-BRCA2 (S3291) Antibody
VS1-YJ15Rabbit Anti-BRCA2 (Phospho S3291) Recombinant Antibody (clone P-CS-4)
MBS8520286-01BRCA2 (phospho Ser3291) Polyclonal Antibody
MBS9511965-01BRCA2 (Phospho-Ser3291) Rabbit Polyclonal Antibody
GTR18288843BRCA2 (Phospho-Ser3291) Polyclonal Conjugated Antibody
TMAC-00472-01Anti-Phospho-BRCA2 (Ser3291) Polyclonal Antibody
E28PP0512BRCA2 (phospho Ser3291) Rabbit Polyclonal Antibody
WP9544-01U-Blot® BRCA2 (phospho Ser3291) Polyclonal Antibody

Popular Products