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USP50 Polyclonal Antibody

CAT: 0965-JOT-AP09449-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP09449-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP50 (ubiquitin specific peptidase 50) is a 339 amino acid protein that belongs to the peptidase C19 family of proteins. Weakly expressed in a few tissues, USP50 contains all of the active residues necessary to function as a deubiquitinating enzyme, but it appears to be catalytically inactive. The gene ecoding USP50 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
CAS Number
9007-83-4
Synonyms
USP50; Inactive ubiquitin carboxyl-terminal hydrolase 50; Inactive ubiquitin-specific peptidase 50
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human USP50. AA range:251-300
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
38955
Antibody Type
Primary antibody
Isotype
IgG

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