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TIMP-1 Polyclonal Antibody

CAT: 0965-JOT-AP09034-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP09034-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TIMP1 belongs to the TIMP gene family.Metalloproteinase inhibitor 1 encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. TIMP1 is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
CAS Number
9007-83-4
Synonyms
TIMP1; CLGI; TIMP; Metalloproteinase inhibitor 1; Erythroid-potentiating activity; EPA; Fibroblast collagenase inhibitor; Collagenase inhibitor; Tissue inhibitor of metalloproteinases 1; TIMP-1
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human TIMP1. AA range:61-110
Clonality
Polyclonal
Applications
IF, WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
23171
Antibody Type
Primary antibody
Isotype
IgG