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TIE-1

CAT: 0209-101-M46Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-101-M46Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TIE-1 (tyrosine kinase with Ig and EGF homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF) -like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis.
Synonyms
TIE1; TIE; JTK14
NCBI Gene ID
7075
UniProt
P35590
Accession Number
NP_005415
Accession Number mRNA
NM_005424
Chromosomal Location
1p34-p33
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human soluble TIE-1
Clone
(#8C9)
Applications
ELISA, WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Bioactivity
ELISA: Use at 1-15 µg/ml; Western blotting: Use at 1-2 µg/ml
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
Notes
The monoclonal antibody will detect native human TIE-1 in ELISA experiments and on the surface of different human cell types. The antibody can be used for ELISA experiments, Western blotting, FACS and cell sorting.
Host or Source
Mouse
Isotype
IgG1

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Alternative Products

CatalogName
337205-01Tie-1
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042827Tie1, ID (Tie1, Tie, Tie-1, Tyrosine-protein kinase receptor Tie-1)
346249-01Tie-1 discontinued
E80805-2TIE-1 Antibody
GWB-7C7BBCTie-1, Antibody
sc-101587Tie-1 (12D9)
MBS6355525-01Tie1, ID (Tie1, Tie, Tie-1, Tyrosine-protein kinase receptor Tie-1) (AP)
abx073608-01Mouse TIE-1 Fc Chimera (TIE-1 Fc) Protein
MBS6355527-01Tie1, ID (Tie1, Tie, Tie-1, Tyrosine-protein kinase receptor Tie-1) (Biotin)

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