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TGFBeta RII Polyclonal Antibody

CAT: 0965-JOT-AP08971-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP08971-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TGFBR2 encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The TGF-beta receptor type-2 is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
CAS Number
9007-83-4
Synonyms
TGFBR2; TGF-beta receptor type-2; TGFR-2; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TbetaR-II
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human TGF beta Receptor II. AA range:91-140
Clonality
Polyclonal
Applications
IF, WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
64568
Antibody Type
Primary antibody
Isotype
IgG

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