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TGase2 Polyclonal Antibody

CAT: 0965-JOT-AP08965-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP08965-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. Protein-glutamine gamma-glutamyltransferase 2 encoded by TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the protein-glutamine gamma-glutamyltransferase 2 is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
TGM2; Protein-glutamine gamma-glutamyltransferase 2; Tissue transglutaminase; Transglutaminase C; TG(C); TGC; TGase C; Transglutaminase H; TGase H; Transglutaminase-2; TGase-2
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Transglutaminase 2. AA range:1-50
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
77329
Antibody Type
Primary antibody
Isotype
IgG

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