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SPOP Polyclonal Antibody

CAT: 0965-JOT-AP08515-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP08515-01Size:20 µL
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Background
SPOP (speckle type BTB/POZ protein) encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1. , a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of SPOP results in multiple transcript variants encoding the same protein.
CAS Number
9007-83-4
Synonyms
Speckle-type POZ protein (HIB homolog 1) (Roadkill homolog 1)
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human SPOP. AA range:41-90
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
42132
Antibody Type
Primary antibody
Isotype
IgG

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