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SnoN Polyclonal Antibody

CAT: 0965-JOT-AP08426-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP08426-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Ski-like protein encoded by SKIL is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
SKIL; SNO; Ski-like protein; Ski-related oncogene; Ski-related protein
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human SKIL. AA range:616-665
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
77004
Antibody Type
Primary antibody
Isotype
IgG