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S2P Polyclonal Antibody

CAT: 0965-JOT-AP08099-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP08099-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MBTPS2 (membrane bound transcription factor peptidase, site 2) encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in MBTPS2 have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.
CAS Number
9007-83-4
Synonyms
MBTPS2; S2P; Membrane-bound transcription factor site-2 protease; Endopeptidase S2P; Sterol regulatory element-binding proteins intramembrane protease; SREBPs intramembrane protease
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human MBTPS2. AA range:301-350
Clonality
Polyclonal
Applications
IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
57444
Antibody Type
Primary antibody
Isotype
IgG

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