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p18 Polyclonal Antibody

CAT: 0965-JOT-AP06747-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP06747-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cyclin dependent kinase inhibitor 2C encoded by CDKN2C is a member of the INK4 family of cyclin-dependent kinase inhibitors. Cyclin dependent kinase inhibitor 2C has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of CDKN2C was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of CDKN2C in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of CDKN2C, which encode an identical protein, have been reported.
CAS Number
9007-83-4
Synonyms
CDKN2C; CDKN6; Cyclin-dependent kinase 4 inhibitor C; Cyclin-dependent kinase 6 inhibitor; p18-INK4c; p18-INK6
Host
Rabbit
Reactivity
Human;Mouse;Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human p18 INK. AA range:111-160
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
18127
Antibody Type
Primary antibody
Isotype
IgG

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