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Oct-3/4 Polyclonal Antibody

CAT: 0965-JOT-AP06333-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP06333-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
POU5F1 encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of POU5F1 in adult tissues is associated with tumorigenesis. POU5F1 can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
CAS Number
9007-83-4
Synonyms
POU5F1; OCT3; OCT4; OTF3; POU domain; class 5, transcription factor 1; Octamer-binding protein 3; Oct-3; Octamer-binding protein 4; Oct-4; Octamer-binding transcription factor 3; OTF-3
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human OCT3. AA range:191-240
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
38571
Antibody Type
Primary antibody
Isotype
IgG

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