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Nephrin Polyclonal Antibody

CAT: 0965-JOT-AP05888-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05888-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NPHS1 encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. NPHS1 is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.
CAS Number
9007-83-4
Synonyms
NPHS1; NPHN; Nephrin; Renal glomerulus-specific cell adhesion receptor
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Nephrin. AA range:843-892
Clonality
Polyclonal
Applications
IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
134742
Antibody Type
Primary antibody
Isotype
IgG

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