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Nectin 1 Polyclonal Antibody

CAT: 0965-JOT-AP05867-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05867-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NECTIN1 encodes nectin cell adhesion molecule 1 that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
CAS Number
9007-83-4
Synonyms
PVRL1; HVEC; PRR1; Poliovirus receptor-related protein 1; Herpes virus entry mediator C; Herpesvirus entry mediator C; HveC; Herpesvirus Ig-like receptor; HIgR; Nectin-1; CD111
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human PVRL1. AA range:81-130
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
57158
Antibody Type
Primary antibody
Isotype
IgG

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