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NCAM-L1 Polyclonal Antibody

CAT: 0965-JOT-AP05801-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05801-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of L1CAM results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.
CAS Number
9007-83-4
Synonyms
Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (CD antigen CD171)
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
Synthetic peptide from human protein at AA range: 151-200
Clonality
Polyclonal
Applications
IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
140003
Antibody Type
Primary antibody
Isotype
IgG

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