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MYSM1 Polyclonal Antibody

CAT: 0965-JOT-AP05743-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05743-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MYSM1 (Myb Like, SWIRM And MPN Domains 1) is a Protein Coding gene. Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. Diseases associated with MYSM1 include hemorrhagic cystitis. Gene Ontology (GO) annotations related to this gene include chromatin binding and protein complex binding. An important paralog of this gene is MPND.
CAS Number
9007-83-4
Synonyms
MYSM1; KIAA1915; Histone H2A deubiquitinase MYSM1; 2A-DUB; Myb-like; SWIRM and MPN domain-containing protein 1
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human MYSM1. AA range:520-569
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
95032
Antibody Type
Primary antibody
Isotype
IgG

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