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MNT Polyclonal Antibody

CAT: 0965-JOT-AP05498-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05498-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. MNT encodes a protein member of the Myc/Max/Mad network. Max-binding protein MNT has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. Max-binding protein MNT is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. Max-binding protein MNT represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.
CAS Number
9007-83-4
Synonyms
MNT; BHLHD3; ROX; Max-binding protein MNT; Class D basic helix-loop-helix protein 3; bHLHd3; Myc antagonist MNT; Protein ROX
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human MNT. AA range:315-364
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
62300
Antibody Type
Primary antibody
Isotype
IgG

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