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MMP-13 Polyclonal Antibody

CAT: 0965-JOT-AP05477-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05477-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MMP13 encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Collagenase 3 in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11.
CAS Number
9007-83-4
Synonyms
MMP13; Collagenase 3; Matrix metalloproteinase-13; MMP-13
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human MMP-13. AA range:10-59
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
53820
Antibody Type
Primary antibody
Isotype
IgG

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