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KV1.1 Polyclonal Antibody

CAT: 0965-JOT-AP04904-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04904-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
KCNA1 encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. Potassium voltage-gated channel subfamily A member 1 has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).
CAS Number
9007-83-4
Synonyms
KCNA1; Potassium voltage-gated channel subfamily A member 1; Voltage-gated K(+) channel HuKI; Voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv1.1
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human KCNA1. AA range:256-305
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
56542
Antibody Type
Primary antibody
Isotype
IgG

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