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KPI-2 Polyclonal Antibody

CAT: 0965-JOT-AP04865-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04865-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The lemur tyrosine kinase 2 encoded by LMTK2 belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis.
CAS Number
9007-83-4
Synonyms
LMTK2; AATYK2; BREK; KIAA1079; KPI2; LMR2; Serine/threonine-protein kinase LMTK2; Apoptosis-associated tyrosine kinase 2; Brain-enriched kinase; hBREK; CDK5/p35-regulated kinase; CPRK; Kinase/phosphat
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human LMTK2. AA range:651-700
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
164900
Antibody Type
Primary antibody
Isotype
IgG

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