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KLHL3 Polyclonal Antibody

CAT: 0965-JOT-AP04845-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04845-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
KLHL3 is ubiquitously expressed and encodes kelch like family member 3 which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
CAS Number
9007-83-4
Synonyms
KLHL3; KIAA1129; Kelch-like protein 3
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human KLHL3. AA range:10-59
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
64970
Antibody Type
Primary antibody
Isotype
IgG

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