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JAM-A Polyclonal Antibody

CAT: 0965-JOT-AP04693-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04693-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. F11 receptor encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
CAS Number
9007-83-4
Synonyms
F11R; JAM1; JCAM; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321
Host
Rabbit
Reactivity
Human;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human F11R. AA range:191-240
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
32583
Antibody Type
Primary antibody
Isotype
IgG