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IRF-4 Polyclonal Antibody

CAT: 0965-JOT-AP04630-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04630-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interferon regulatory factor 4 encoded by IRF4 belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
CAS Number
9007-83-4
Synonyms
IRF4; MUM1; Interferon regulatory factor 4; IRF-4; Lymphocyte-specific interferon regulatory factor; LSIRF; Multiple myeloma oncogene 1; NF-EM5
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human IRF4. AA range:281-330
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
47219
Antibody Type
Primary antibody
Isotype
IgG

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