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IL-17R Alpha Polyclonal Antibody

CAT: 0965-JOT-AP04455-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04455-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IL17RC encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, Interleukin-17 receptor C is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.
CAS Number
9007-83-4
Synonyms
Interleukin-17 receptor A (IL-17 receptor A) (IL-17RA) (CDw217) (CD antigen CD217)
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from human IL-17Rα
Clonality
Polyclonal
Applications
IHC-p, WB
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
86294
Antibody Type
Primary antibody
Isotype
IgG

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