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IGF-IR Polyclonal Antibody

CAT: 0965-JOT-AP04397-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04397-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IGF1R, this receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
Synthesized peptide derived from IGF-IR . at AA range: 1100-1180
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
154793
Antibody Type
Primary antibody
Isotype
IgG

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