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IFITM2 Polyclonal Antibody

CAT: 0965-JOT-AP04354-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04354-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IFITM2 (Interferon Induced Transmembrane Protein 2) is a Protein Coding gene. Diseases associated with IFITM2 include west nile virus and stomatitis. Among its related pathways are Immune System and Interferon gamma signaling. An important paralog of this gene is IFITM1. IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.
CAS Number
9007-83-4
Synonyms
IFITM2; Interferon-induced transmembrane protein 2; Dispanin subfamily A member 2c; DSPA2c; Interferon-inducible protein 1-8D
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human IFITM2. AA range:1-50
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
14632
Antibody Type
Primary antibody
Isotype
IgG

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