Products for Research Use Only
RegisterLogin

HMP19 Polyclonal Antibody

CAT: 0965-JOT-AP04150-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0965-JOT-AP04150-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The chondroitin sulfate proteoglycan NG2 is a type I membrane protein expressed by subpopulations of glia including oligodendroglial precursor cells and a variety of tumor cells. Normal precursor cells and malignant tumor cells migrate and proliferate, but there is evidence that cells may not be able to engage in both activities at the same time. However, NG2 is involved in promoting both proliferation and motility. The extracellular domain of NG2 sequesters growth factors and binds to both growth factor receptors and extracellular matrix ligands such as fibronectin, collagens and laminin. The cytoplasmic domain is involved in activating Rac, Cdc42 and p130 Cas. PKCα phosphorylates NG2 at Thr2256, triggering the redistribution of NG2 from apical microprocesses to lamellipodia accompanied by enhanced cell motility. ERK phosphorylates NG2 at Thr2314, stimulating cell proliferation.
CAS Number
9007-83-4
Synonyms
NSG2; Neuron-specific protein family member 2; Protein p19; Hmp19
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human NSG2. AA range:33-82
Clonality
Polyclonal
Applications
IHC-p, WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
19085
Antibody Type
Primary antibody
Isotype
IgG

Related Products

CatalogName
JOT-AP15592-01YTHD2 Polyclonal Antibody
JOT-AP15626-01ZEB1 Polyclonal Antibody
JOT-AP15515-01VWA3A Polyclonal Antibody
JOT-AP15563-01WWTR1 Polyclonal Antibody
JOT-AP15568-01XDH Polyclonal Antibody
JOT-AP15664-01ZN713 Polyclonal Antibody
JOT-AP15660-01ZN574 Polyclonal Antibody
JOT-AP15554-01WNT7B Polyclonal Antibody
JOT-AP15651-01ZN281 Polyclonal Antibody
JOT-AP15702-01ZNRF1 Polyclonal Antibody

Alternative Products

CatalogName
UB-GEN-16152HMP19 Polyclonal Antibody
NBP2-49217-25ulRabbit Polyclonal HMP19 Antibody
APRab12121-01HMP19 Rabbit Polyclonal Antibody
TA315489NSG2 (HMP19) Rabbit Polyclonal Antibody
WP12707-01U-Blot® HMP19 Polyclonal Antibody
PA89953HU-01Rabbit Anti-Human HMP19 Polyclonal Antibody
PAV7958Rabbit Anti-HMP19/NSG2 Polyclonal Antibody
C17010-01HMP19 Antibody
A33961Anti-HMP19 Antibody
abx233939Neuron-Specific Protein Family Member 2 (HMP19) Antibody

Popular Products