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HisRS Polyclonal Antibody

CAT: 0965-JOT-AP03978-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP03978-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Histidine--tRNA ligase cytoplasmic encoded by HARS is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for HARS.
CAS Number
9007-83-4
Synonyms
HARS; HRS; Histidine--tRNA ligase; cytoplasmic; Histidyl-tRNA synthetase; HisRS
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human HARS. AA range:460-509
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
57411
Antibody Type
Primary antibody
Isotype
IgG

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