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GPR172A Polyclonal Antibody

CAT: 0965-JOT-AP03717-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP03717-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SLC52A2 (solute carrier family 52 member 2) encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, SLC52A2 has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in SLC52A2 have been associated with Brown-Vialetto-Van Laere syndrome 2--an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia.
CAS Number
9007-83-4
Synonyms
SLC52A2; GPR172A; PAR1; RFT3; Solute carrier family 52; riboflavin transporter, member 2; Porcine endogenous retrovirus A receptor 1; PERV-A receptor 1; Protein GPR172A; Riboflavin transporter 3; hRF
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human PEVR1. AA range:43-92
Clonality
Polyclonal
Applications
WB, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
45777
Antibody Type
Primary antibody
Isotype
IgG

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