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GCP4 Polyclonal Antibody

CAT: 0965-JOT-AP03517-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP03517-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TUBGCP4 encodes a component of the gamma-tubulin ring complex, gamma-tubulin complex component 4, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
TUBGCP4; 76P; GCP4; Gamma-tubulin complex component 4; GCP-4; hGCP4; Gamma-ring complex protein 76 kDa; h76p; hGrip76
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human TUBGCP4. AA range:191-240
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
76089
Antibody Type
Primary antibody
Isotype
IgG