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FOP Polyclonal Antibody

CAT: 0965-JOT-AP03302-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP03302-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FGFR1OP encodes a largely hydrophilic centrosomal protein, FGFR1 oncogene partner, that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.
CAS Number
9007-83-4
Synonyms
FGFR1OP; FOP; FGFR1 oncogene partner
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human FGFR1 Oncogene Partner. AA range:341-390
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
43065
Antibody Type
Primary antibody
Isotype
IgG