Products for Research Use Only
RegisterLogin

Factor I Polyclonal Antibody

CAT: 0965-JOT-AP03122-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0965-JOT-AP03122-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
CFI encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uremic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immune deposits and age-related macular degeneration are other conditions associated with mutations of this gene.
CAS Number
9007-83-4
Synonyms
CFI; IF; Complement factor I; C3B/C4B inactivator
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human CFI. AA range:441-490
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
65720
Antibody Type
Primary antibody
Isotype
IgG

Related Products

CatalogName
JOT-AP00590-01Arginase I Polyclonal Antibody
JOT-AP08707-01Synapsin I Polyclonal Antibody
JOT-AP00645-01Arylsulfatase I Polyclonal Antibody
JOT-AP05934-01Neurophysin I Polyclonal Antibody
JOT-AP04603-01IP3R-I Polyclonal Antibody
JOT-AP02961-01Endophilin I Polyclonal Antibody
JOT-AP06278-01Annexin I Polyclonal Antibody
JOT-AP08525-01I-FABP Polyclonal Antibody
JOT-AP15066-01Collagen I Polyclonal Antibody
JOT-AP06259-01ANG I Polyclonal Antibody

Alternative Products

CatalogName
A312Factor H Antibody (Polyclonal)
A314Factor D Antibody (Polyclonal)
A311Factor B Antibody (Polyclonal)
MBS2555425-01Factor XIIIa Polyclonal Antibody
MBS9246415-01Factor IX Polyclonal Antibody
MBS9243615-01Factor VIII Polyclonal Antibody
bs-4690R-TRTissue factor Polyclonal Antibody
bs-1587R-TRFactor XIII Polyclonal Antibody
MBS9233830-01factor V Polyclonal Antibody
BS90490Factor H polyclonal antibody

Popular Products