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CtIP Polyclonal Antibody

CAT: 0965-JOT-AP02300-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02300-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by RBBP8 (RB binding protein 8, endonuclease) is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that RBBP8 may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for RBBP8. More transcript variants exist, but their full-length natures have not been determined.
CAS Number
9007-83-4
Synonyms
RBBP8; CTIP; DNA endonuclease RBBP8; CtBP-interacting protein; CtIP; Retinoblastoma-binding protein 8; RBBP-8; Retinoblastoma-interacting protein and myosin-like; RIM; Sporulation in the absence of SP
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human RBBP8. AA range:630-679
Clonality
Polyclonal
Applications
IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
101942
Antibody Type
Primary antibody
Isotype
IgG

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