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COL4A4 Polyclonal Antibody

CAT: 0965-JOT-AP02085-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02085-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
COL4A4 encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. This particular collagen IV subunit, however, is only found in a subset of basement membranes. Like the other members of the type IV collagen gene family, COL4A4 is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease). Two transcripts, differing only in their transcription start sites, have been identified for this gene and, as is common for collagen genes, multiple polyadenylation sites are found in the 3' UTR.
CAS Number
9007-83-4
Synonyms
COL4A4; Collagen alpha-4(IV) chain
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human Collagen IV alpha4. AA range:541-590
Clonality
Polyclonal
Applications
IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
163999
Antibody Type
Primary antibody
Isotype
IgG

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