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CHD1L Polyclonal Antibody

CAT: 0965-JOT-AP01746-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP01746-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CHD1L encodes a DNA helicase protein involved in DNA repair. The chromodomain-helicase-DNA-binding protein 1-like converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have been described for this gene. CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like) is a Protein Coding gene. Diseases associated with CHD1L include fibrosarcoma of bone. Among its related pathways are Chromatin Regulation / Acetylation and DNA Double-Strand Break Repair. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and hydrolase activity. DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding.
CAS Number
9007-83-4
Synonyms
CHD1L; ALC1; Chromodomain-helicase-DNA-binding protein 1-like; Amplified in liver cancer protein 1
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human CHD1L. AA range:545-594
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
101000
Antibody Type
Primary antibody
Isotype
IgG

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