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c-Fgr Polyclonal Antibody

CAT: 0965-JOT-AP01717-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP01717-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FGR is a member of the Src family of protein tyrosine kinases (PTKs). The FGR proto-oncogene, Src family tyrosine kinase contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
CAS Number
9007-83-4
Synonyms
FGR; SRC2; Tyrosine-protein kinase Fgr; Gardner-Rasheed feline sarcoma viral; v-fgr) oncogene homolog; Proto-oncogene c-Fgr; p55-Fgr; p58-Fgr; p58c-Fgr
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human FGR. AA range:381-430
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
59479
Antibody Type
Primary antibody
Isotype
IgG

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